DETAILS:
Tesofensine is a triple monoamine reuptake (TMRI) inhibitor It works by increasing the levels of serotonin, norepinephrine, and dopamine in the brain, which helps to suppress appetite and enhance satiety. It is being currently used for the treatment obesity and supporting weight loss.
- Mechanism of Action: Tesofensine blocks the reuptake of dopamine, norepinephrine, and serotonin in the brain, particularly in the hypothalamus, the region that controls hunger and energy balance. This action leads to reduced appetite, enhanced satiety, and potentially increased metabolic rate.
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